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BUSINESS STORIES

OPERATIONAL REVIEW


 
treatment. According to guidelines from governmental and professional groups such as the (US) Agency for Health Care Policy and Research, and the European Pressure Ulcer Advisory Panel, poor nutrition is a major risk factor for development and progression of wounds, including pressure ulcers and diabetic foot ulcers.
Inadequate nutrition can make body tissue more susceptible to the effects of pressure, resulting in greater risk for wound development, and slow healing. Moreover, the aging process itself is associated with reduced appetite and overall intake, putting elderly long-term care residents at greater risk for malnutrition. Adequate medical nutrition therapy or dietary intake of calories, protein and fluids – along with key nutrients – is a cost-effective strategy to prevent and treat pressure ulcers, with the potential to significantly accelerate healing.
For years, Novartis Medical Nutrition has provided patients and physicians with RESOURCE Arginaid EXTRA drinks – an easy and convenient way to provide the specific nutrients that help wound healing. These nutrients range from zinc and vitamins C and E, to arginine, an amino acid that works at the cellular level to help promote wound healing.
Last year Novartis Medical Nutrition launched the product in Japan, under the Isocal Arginaid brand, as the first oral supplement specifically targeting wound care. The success of the launch reflected the consumer insights used by the Medical Nutrition Business Unit to adapt Isocal Arginaid to the Japanese diet and taste.
Compared to Western countries, the Japanese diet traditionally is lower in fat content, but higher in levels of protein, zinc and
other micronutrients. “So we adapted the core components of Isocal Arginaid to the nutritional profile and habits of the Japanese consumer,” says Michel Gardet, Head of the Medical Nutrition Business Unit.
Isocal Arginaid was launched in raspberry and orange flavors already available in Western markets – but the taste is milder, in line with local preferences. Novartis Medical Nutrition also is preparing the launch of two additional flavors – green apple and grape – that are popular with seniors in Japan.
The flavors are designed to go with foods usually eaten for breakfast and the main meal of the day. And while Isocal Arginaid comes in a ready-to-serve brik package, the volume is reduced to 125 milliliters, or about half the size of the standard US brik pack.
Catering to local consumers seems to be paying off, especially in terms of compliance. In pilot studies in Japanese hospitals and geriatric institutions, almost 90% of participating patients finished the Isocal Arginaid drinks served with their meals.

THE CATNIP PILL
Fortekor, the daily treatment for chronic renal insufficiency in cats from Novartis Animal Health, is one of the first veterinary medicines to address the needs of both cats and their owners. Fortekor pills are oval in shape – an unconventional design that reflects two fundamental consumer insights.
Animals don't understand that a medicine is good for them. Cats compound the difficulty of drug treatment because as notoriously finicky eaters they may bite pills, rather than swallow them, and consequently lose part of the intended dose.
To ensure correct dosing, an owner often has to force the medicine down the animal’s throat. Yet many pet owners simply won’t force-feed medication for fear of damaging the trusting relationship they have established with their pet. In the case of Fortekor – indicated for a chronic disease and requiring daily administration – that challenge is magnified.
Novartis scientists hit upon a solution by using innovation – not force. Extensive tests of diverse tablet shapes showed that a soft, oval tablet is easier for cats to swallow – by being slimmer at its widest point than the diameter of a comparable round pill. In addition, Fortekor was transformed to sheer catnip by varying texture of the tablet and adding a flavor.
In home tests involving hundreds of owners and their pets, almost 90% of cats voluntarily took the oval, flavored Fortekor tablet – compared to only about 50% of cats given a conventional round pill.
The shape, texture and taste of animal medication is a relief for owners, ensuring correct and regular dosing to achieve the desired therapeutic effect, while strengthening the relationship with their pets. Buoyed by the success of the new Fortekor, Novartis Animal Health has developed and launched formulations of other medications applying the same principle.

 

NOVARTIS GROUP BUSINESS REVIEW 2005